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Soft Tissue Sarcomas

They are rare cancerous tumors that can grow in:

  • Blood vessels
  • Fat
  • Muscle
  • Nerves

About half of all soft-tissue sarcomas appear in the arms and legs. The rest appear in the head, neck, or trunk.

Our doctors have a vast amount of experience in the diagnosis and treatment of many types of soft-tissue sarcomas, including: 

  • Angiosarcoma of bone develops from the blood vessels and typically affects the long bones of the body. These tumors most frequently affect adults who are 60 and older.
  • Hemangioendothelioma develops in the epithelial cells, which line the inside of blood vessels. These tumors affect the soft tissues, liver, lungs, and bones.
  • Hemangiopericytoma develops in the brain, pelvis, head, and neck, though the tumors can be found anywhere in the body where blood vessels are present. These tumors can be benign or cancerous.
  • Hemangiosarcoma develops from the blood vessels in the arms, legs, head, and trunk.
  • Leiomyosarcoma develops from smooth muscles used to control the movement of internal organs and blood vessels. These tumors tend to affect adults.
  • Liposarcoma develops from fatty tissues and appears most often in the legs and trunk.
  • Lymphangiosarcoma develops from the lymph vessels and appears in the arms. It tends to affect tissues that may have been exposed to radiation.
  • Fibrosarcoma and malignant fibrous histiocytoma develops in the tendons, ligaments, fat, or muscle that surround the bones and affects the arms, legs, or jaw. It is most common in older adults.
  • Neurofibrosarcoma develops from nerves and appears most often in the legs, arms, and trunk.
  • Radiation induced sarcoma develops in patients who have had previous radiation therapy. This sarcoma typically appears within 10 years of radiation therapy and tends to be considered a high-grade or more aggressive type of tumor.
  • Rhabdomyosarcoma develops from skeletal muscles used to move bones. It tends to affect young children and appears most often in the arms and legs.
  • Synovial sarcoma develops from tissues that cushion the joints, such as knees and elbows. It tends to affect children and teens.


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Do you have a family history of orthopedic cancer? Do you need a second opinion or more advanced care? Please call us.



Our Locations

Orthopedic Cancer at MedStar Franklin Square Medical Center
The Harry and Jeanette Weinberg Cancer Institute
The National Center for Bone and Soft Tissue Tumors
9103 Franklin Square Dr., Ste. 2200
Baltimore, MD 21237

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